Droplet Manipulation Technologies

Droplet Manipulation Technologies 

Droplet manipulation technologies have been developed in the past decades since its invention, however, some of the functions that are critical for conventional biological investigation still remain unachieved. We have enabled a list of droplet manipulation technologies that can be implemented into the droplet microfluidic system to improve its applicability. Additionally, we have also invented some novel approaches to manipulate the droplets, with higher efficiencies.

 

Selected Project/Publications

1. Han Zhang et al. ,FIDELITY: A quality control system for droplet microfluidics.Sci. Adv.8,eabc9108(2022).DOI:10.1126/sciadv.abc91082.
2. C. Huang, H. Zhang, S. -I. Han, and A. Han, Cell Washing and Solution Exchange in Droplet Microfluidic Systems, Analytical Chemistry, Vol. 93 (24), 8622-8630 (2021)
3. H. Zhang*, A. Guzman*, J. Wippold, Y. Li, J. Dai, C. Huang, and A. Han (*these authors contributed equally), An Ultra High-Efficiency Droplet Microfluidics Platform using Automatically Synchronized Droplet Pairing and Merging, Lab on a Chip, Vol. 20, pp. 3948-3959(2020)
4. S. Han*, C. Huang*, and A. Han (*these authors contributed equally), In-droplet Cell Separation based on Bipolar Dielectrophoretic Response to Facilitate Cellular Droplet Assays, Lab on a Chip, Vol. 20, pp. 3832-3841 (2020)
5. S. Han, H. Kim, and A. Han, In-Droplet Cell Concentration using Dielectrophoresis, Biosensors and Bioelectronics, Vol. 97, pp. 41-45 (2017)