NanoBio Systems Lab

Total active projects: over $80 Million

Major active projects:

– Engineered bacteria as cancer therapeutics (ARPA-H, $20 Million)
– Mitigating microbial corrosion (DARPA BTO, $11.6 Million)
– Microbial pathogen detection (DARPA BTO, $16 Million)
– Anti-viral discovery microfluidics (NIH R01, $3.4 Million)
– Clinical Trials on a chip (NIH/NCATS, $3.8 Million)
– Plastic degradation and reutilization (NSF, $2.2 Million)
– and many more

Sponsors:

Recent news

Oct 24, 2025

Congratulation, our collaborative paper with Dr. Ivan Rusyn, “Fetal response to maternal exposures of environmental chemicals: Utility of a four-cell human feto-maternal interface organ-on-chip,” has been published in the Journal of the Chemico-Biological Interections. Link to the article.

Oct 20, 2025

Congratulation, our collaborative paper with Dr. Younghak Cho, “Acousto-viscoelastic droplet microfluidics enhancing single particle-in-droplet encapsulation unlimited by the Poisson distribution,” has been published in the journal of Sensors and Actuators B: Chemical. Link to the article.

Sep 26, 2025

Congratulations, our collaborative paper with Dr. Ching-Chou Wu, “A Label-Free Droplet Sorting Platform Integrating Dielectrophoretic Separation for Estimating Bacterial Antimicrobial Resistanc,” has been published in the journal of Biosensors. Link to the article.

Sep 12, 2025

Congratulations, Haemin Jung, Han Zhang, Jacob Hooper, Can Huang, Rohit Gupte, Adrian Guzman, and Jeong Jae Han! Our paper, “Size-independent and automated single-colony-resolution microdroplet dispensing” has been published in the journal of Lab on a Chip. Link to the article.

May 14, 2025

Congratulations, Rahul Cherukuri! Our collaborative paper with Dr. Menon’s Lab, “Exosomal Delivery of Interleukin-10 Reduces Infection-Associated Inflammation in a 3D-Printed Model of a Humanized Feto-Maternal Interface,” has been published in FASEB Journal. Link to the article.

April 25, 2025

Congratulation, Yuwen Li, Jing Dai, Han Zhang, Adrian Guzman, and Song-I Han. Their paper, “Rapid filamentous fungi gene knockout identification through high-throughput droplet microfluidics” has been published in the journal of Analytica Chimica Acta. Link to the journal article.

March 27, 2025

Nanobio System Laboratory members participated a seminar discussing Electrochemical Sensing given by Professor Ching-Chou Wu from the University Academic Alliance in Taiwan (UAAT). Thank you for a fantastic special seminar, Professor Ching-Chou Wu!

March 25, 2025

Congratulation, Nina Truong, Abir Zahra, Ryan C. V. Lintao, Rahul Chauhan, Giovana Fernanda Bento, Manuel Vidal Jr., Sungjin Kim, Po Yi Lam, Thomas Conracts, Kelly Conrads, Arum Han, Ramkumar Menon, and Lauren S. Richerdson. Their paper, “Modeling reproductive and pregnancy-associated tissues using organ-on-chip platforms: challenges, limitations, and the high throughput data frontier” has been published in the journal of Frontiers in Bioengineering and Biotechnology. Link to the journal article.

March 11, 2025

Congratulation, Sourabh Sharma, Manuel Vidal, Souvik Paul, Arum Han, Ramkumar Menon, and Lauren S. Richardson. Their paper, “The effect of Polybrominated diphenyl ethers at the fetal blood-brain-barrier: evaluation using a microphysiological system” has been published in the journal of Frontiers in Cell and Developmental Biology. Link to the journal article.

March 10, 2025

Congratulation, Jinha Kim, Arum Han, and Kung-Hui Chu. Their paper, “Draft genomes of three bacteria capable of growing on cocamidopropyl betaine or N,N,N-trimethylglycine (betaine): Cupriavidus sp. CuC1, Variovorax sp. VaC1, and Pseudomonas sp. PsB” has been published in the journal of Microbiology Resource Announcements. Link to the journal article.