NanoBio Systems Lab.
The NanoBio Systems Laboratory is interested in solving grand challenges in the areas of healthcare and energy through the use of micro/nano systems technology. Our effort is multidisciplinary, encompassing expertise from engineering (electrical, biomedical, mechanical, chemical, computer), physical science (chemistry), and life sciences (neuroscience, microbiology, cancer biology, biochemistry, plant pathobiology, veterinary medicine, agriculture).
Our current research themes are: accelerating the development of therapeutics and vaccines against emerging infectious diseases through microfluidic and lab-on-a-chip technologies, developing methods to detect and identify pathogenic microorganisms, developing and utilizing microorganisms as refineries for bioproduction through a combination of synthetic biology and high-throughput microfluidics, developing microphysiological systems (i.e., organ-on-a-chip, tissue chip) especially for preterm birth and neurobiology applications, and developing broad ranges of high-throughput single-cell assay microfluidic platforms.
Room 216: Dry lab for microfabrication (soft-lithography, hot embossing), imaging and rapid prototyping.
Room 132: BL2 wet lab for feto-maternal interface cell lines related research, such as environmental toxicant exposure study, air pollutant study, 3D bio printing, and Organ-on-Chip platform development. *Room 132-A: dedicated for cell maintenance.
Room 133: BL2 wet lab for microorganisms (pathogens, microbiome, fungi, and virus ) & mammalian cell biology (human MCS, cancer cell line, primary cancer cell) related research, such as live cell imaging, hypoxic co-cultivation, molecular biology, high throughput screening and sensing, high frame rate imaging, and automation
Key core facilities
AggieFab
The Institute of Solid State Electronics (ISSE) cleanroom at Texas A&M is a new 5000 sq. ft. class 100 and 1000 cleanroom, located in the Jack E. Brown building. The facility houses state of the art micro and nano fabrication equipments (Mask aligner, spinner, metal evaporator, RIE, PECVD, oxidation/diffusion furnaces, wire bonder, dicing saw, polisher) and various analysis equipments (Microscope, profilometer, ellipsometer, probe station). The facility has multiple chemical hoods and laminar hoods and is equipped with in-house de-ionized water, vacuum, and nitrogen.
Material Characterization Facility (MCF)
The Material Characterization Facility (MCF) located in the 1st floor of the Frederick E. Giesecke Engineering Research Building has various fabrication equipments (Mask aligner, spin coater, RIE, metal evaporator, wire bonder) and Characterization equipments (XPS, nanoindenter, 3D microscope, profilometer, and a confocal microscope).
Microscopy and Imaging Center (MIC)
The Microscopy and Imaging Center (MIC) at Texas A&M is another multiuser facility that has multiple confocal and fluorescent microscopes, three SEMs, an AFM, and two TEMs. The PI has access to this facility. The Biomedical Engineering Department has a common cell culture facility equipped with bio-hoods, incubators, fluorescent microscopes.