NanoBio Systems Lab

Texas A&M University

High-throughput Screening

High-throughput Screening

Droplet microfluidic platforms, with a certain degree of modification, can fit to serve a variety of high-throughput screening applications. We have been focused to develop various droplet microfluidic systems to screen rare cells of interest from a heterogenous library, such as neutralizing antibody-producing B cells, corrosion-resistive microbial, and high-yield biofuel cells, to name a few.

 

Selected Project/Publications

  1. J. A. Wippold, H. Wang, J. Tingling, J. L. Leibowitz, P. de Figueiredo, and A. Han, PRESCIENT: Platform for the Rapid Evaluation of Antibody Success using Integrated Microfluidics Enabled Technology,Lab on a Chip, Vol. 20, pp. 1628-1638 (2020)
  2. Corrosive (Han Zhang)
  3. H. S. Kim, S. –C. Hsu, S. –I. Han, H. R. Thapa, A. R. Guzman, D. R. Browne, M. Tatli, T. P. Devarenne, D. B. Stern, and A. Han, A High-Throughput Droplet Microfluidics Screening Platform for Selecting Fast Growing and High Lipid Producing Microalgae from a Mutant Library, Plant Direct, Vol. 1 (3), pp. 1-13 (2017)
  4. H. S. Kim*, S. C. Waqued*, D. T. Nodurft, T. P. Devarenne, V. V. Yakovlev, and A. Han (*these authors contributed equally), Raman Spectroscopy Compatible PDMS Droplet Microfluidic Culture and Analysis Platform towards On-Chip Lipidomics, Analyst, Vol. 142, pp. 1054-1060 (2017)
  5. H. S. Kim, A. R. Guzman, H. R. Thapa, T. P. Devarenne, and A. Han, A Droplet Microfluidics Platform for Rapid Microalgal Growth and Oil Production Analysis, Biotechnology and Bioengineering, Vol. 113 (8), pp. 1691-1701 (2016).