Mutant Selection
Enriching/selecting outliners from a homogenous library can help the overall population to promote their overall desired phenotypes. We have participated in various projects focusing on the selection/enrichment of preferred subpopulations, for increasing the speed of plastic degradation, selecting binding materials with higher affinity; investigating the mechanism of high intracellular properties, to name a few.
Selected Project/Publications
- Plastic degradation (SH)
- S. Han*, H. S. Kim*, K. -H. Han, and A. Han (*these authors contributed equally), Digital quantification and selection of high-lipid-producing microalgae through a lateral dielectrophoresis-based microfluidic platform, Lab on a Chip, Vol. 19, pp. 4128-4138 (2019)
- C. Huang, F. Guo, H. Wang, J. Olivares, J. Dalton, III, O. Belyanina, A. R. Wattam, C. A. Cucinell, A. W. Dickerman, Q. Qin, A. Han and P. de Figueiredo, An automated system for interrogating the evolution of microbial endosymbiosis, Lab Chip, 2023, 23, 671
- S. -I. Han*, D. A. Sarkes*, J. P. Jahnke, M. M. Hurley, V. M. Ugaz, R. Renberg, J. J. Sumner, D. N. Stratis-Cullum, and A. Han (*these authors contributed equally), Discovery of Targeted Material Binding Microorganisms using a Centrifugal Microfluidic Platform, Advanced Materials Technologies, Vol. 6, 2100282 (2021)
- H. S. Kim, T. P. Devarenne and A. Han, A High-Throughput Microfluidic Single-Cell Screening Platform Capable of Selective Cell Extraction, Lab on a Chip, Vol. 15, pp. 2467-2475 (2015)